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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Trends Endocrinol Metab. 2015 Oct 29;26(12):699–710. doi: 10.1016/j.tem.2015.09.005

Figure 3. fasting-related TF cistromes are clustered together in specific, motif-rich hot-spots.

Figure 3

When examining the motifs enriched in a TF cistrome and comparing different cistromes, the observation wass made that fasting-related TFs tend to bind in the same regions. Horizontal rectangles represent a binding motif sequence found to be enriched in a given cistrome. Diagonal rectangles represent a TF with increased binding at a given cistrome.(C/EBP - CCAAT enhancer binding protein, CREB - cAMP responsive element binding protein, ERR - estrogen-related receptor, FoxA – forkhead box transcription factor class A, FoxO –forkhead box transcription factor class O, GR – glucocorticoid receptor, HNF - hepatocyte nuclear factor, PPARα - peroxisome proliferator-activated receptor α, TR – thyroid hormone receptor)