Table 3.
Pooled sensitivity and specificity of diabetes diagnosis using different definitions among participants without diagnosed diabetes
| Number of surveys | Sensitivity | Specificity | |||
|---|---|---|---|---|---|
| (%; 95% CI) | I2 | (%; 95% CI) | I2 | ||
| HbA1cvs FPG | 27 | 52·82 (51·33–54·30) | 97·6% | 99·74 (99·71–99·78) | 98·2% |
| HbA1cvs 2hOGTT | 9 | 37·16 (35·05–39·28) | 97·6% | 99·84 (99·79–99·89) | 97·3% |
| HbA1cvs FPG-or-2hOGTT | 9 | 30·46 (28·66–32·25) | 97·9% | 99·69 (99·63–99·76) | 98·0% |
| FPG vs 2hOGTT | 33 | 54·42 (53·26–55·57) | 96·9% | 98·90 (98·83–98·97) | 94·4% |
The appendix shows detailed results of these meta-analyses. Diabetes was defined as HbA1c ≥6·5%, FPG ≥7·0 mmol/L, and 2hOGTT ≥11·1 mmol/L. FPG=fasting plasma glucose. 2hOGTT=2-h oral glucose tolerance test.