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. 2015 Jun 15;6(26):21950–21963. doi: 10.18632/oncotarget.4277

Figure 5. Schematic representation of protein–protein interaction network involving Rab GTPases.

Figure 5

Shown are protein–protein interaction networks from in NAViGaTOR using I2D and the Reactome, BioCarta and KEGG databases assessing functional interactions. High connectivity (k > 20 ) was highlighted by different shapes. GO term enrichment of proteins is rendered by node color. Node shapes indicate the involved process: cell adhesion genes (circle), epithelial-mesenchymal transition genes (square), inflammatory related-genes (diamond). Solid blue edges describe the interactions between well-described enriched genes in each assessed process and neighborhood. Enrichment of proteins involved in cell adhesion genes (blue circle), inflammatory related-genes (green circle) and epithelial-mesenchymal transition genes (pink circle) were observed (P < 0.01).