Table 5. Shared Cell Pathways and Cellular Processes Linked to Genes with CAML.

Common Cell Pathways Linked to Genes with CAML Genotypes Shared by BC & NTC/NCC Lineage Cancers
Disease Comparisons	p-value	Canonical Pathway	Top Networks
BC-GBM	-	-	Carbohydrate Metabolism, Small Molecule Biochemistry, Cardiovascular Disease
BC-LGG	8.0 × 10−3	VDR/RXR Activation TR/RXR Activation	DNA Replication, Recombination, and Repair, Energy Production, Nucleic Acid Metabolism
BC-MB	3.2 × 10−3	Regulation by Calpain Protease	Lipid Metabolism, Small Molecule Biochemistry, Cellular Movement
BC-MEL	1.3 × 10−2	Regulation by Calpain Protease	DNA Replication, Recombination, and Repair, Energy Production, Nucleic Acid Metabolism
	1.6 × 10−2	VDR/RXR Activation TR/RXR Activation

Genes with functions important to Ca²⁺ transport and regulation were identified with BC and LGG, MB, or MEL; no pathways were identified with GBM. The comparison between BC-MEL was not significant though similar to the other pair-wise comparisons described. Multiple networks were described with these associations with small molecule biochemistry, nucleic acid metabolism, and energy production being the most common. P-value describes significance with (p < 0.01).