Table 1. Characteristics of patients according to HPV mRNA status of sentinel lymph nodes (n=189).
| HPV mRNA status of sentinel lymph nodes | Total n = 189 (100.0 %) | |||
|---|---|---|---|---|
| Positive n = 52 (27.5%) | Negative n = 119 (63.0%) | Probably negative n = 18 (9.5%) | ||
| Age [years] | ||||
| Median | 42.5 | 39.0 | 36.5 | 40.0 |
| Range | 22 - 76 | 23 - 77 | 26 - 61 | 22 - 77 |
| BMI [kg/m2]* | ||||
| Median | 24.8 | 23.8 | 22.9 | 24.0 |
| Q1 – Q3 | 22.6 – 27.3 | 22.0 – 26.7 | 21.3 – 24.0 | 21.9 – 26.6 |
| Histology, n (%) | ||||
| Squamous cell ca | 41 (78.8) | 97 (81.5) | 14 (77.8) | 152 (80.4) |
| Adenocarcinoma | 7 (13.5) | 19 (16.0) | 3 (16.7) | 29 (15.3) |
| Others | 4 (7.7) | 3 (2.5) | 1 (5.6) | 8 (4.2) |
| Tumor size [mm]*, n (%) | ||||
| ≤ 20 | 17 (32.7) | 75 (63.0) | 10 (58.8) | 102 (54.0) |
| >20 to 40 | 28 (53.8) | 30 (25.2) | 5 (29.4) | 63 (33.3) |
| >40 | 7 (13.5) | 14 (11.8) | 2 (11.8) | 23 (12.2) |
| Grading*, n (%) | ||||
| G1 | 5 (9.6) | 11 (9.7) | 0 (0.0) | 16 (8.7) |
| G2 | 20 (38.5) | 53 (46.9) | 12 (66.7) | 85 (46.4) |
| G3 | 27 (51.9) | 49 (43.4) | 6 (33.3) | 82 (44.8) |
| HPV type primary tumor, n (%) | ||||
| 16 | 25 (48.1) | 74 (62.2) | 12 (66.7) | 111 (58.7) |
| 18 | 16 (30.8) | 23 (19.3) | 2 (11.1) | 41 (21.7) |
| Others | 11 (21.2) | 22 (18.5) | 4 (22.2) | 37 (19.6) |
Abbreviations: BMI – body mass index, Q1 – first quartile, Q3 – third quartile, ca. – cancer
*
Missing values BMI (n = 39), tumor size (n = 1), grading (n = 6)