Table 2. Expression of seven biomarkers in primary versus metastatic melanomas.
| Biomarker | Primary melanoma No. (%) |
Metastatic melanoma No. (%) |
P value | |||
|---|---|---|---|---|---|---|
| − | + | − | + | Univariate | Multivariate | |
| BRAF | 79 (54.48) | 66 (45.52) | 36 (34.29) | 69 (65.71) | 0.002 | 0.037 |
| Dicer | 10 (6.90) | 135 (93.10) | 23 (21.90) | 82 (78.10) | 0.001 | 0.053 |
| Fbw7 | 22 (15.17) | 123 (84.83) | 21 (20.00) | 84 (80.00) | 0.318 | 0.666 |
| KAI1 | 96 (66.21) | 49 (33.79) | 100 (95.24) | 5 (4.76) | 4.000E-8 | 6.321E-5 |
| MMP2 | 102 (70.34) | 43 (29.66) | 63 (60.00) | 42 (40.00) | 0.089 | 0.166 |
| P27 | 73(50.34) | 72(49.66) | 82(78.10) | 23(21.90) | 8.130E-6 | 9.677E-5 |
| Tip60 | 30(20.69) | 115(79.31) | 46(43.81) | 59(56.19) | 8.768E-6 | 0.029 |