Table 8. Multivariate Cox proportional hazard regression analysis in combined cohort (237 primary melanoma patients) for combined KAI1-/p27- signature.
| Hazard Ratio | 95% CI | P value | |
|---|---|---|---|
| Age: > 60 vs ≤ 60 y | 1.277 | 0.727-2.244 | 0.394 |
| Gender: male vs female | 0.894 | 0.523-1.486 | 0.665 |
| Thickness: > 2 vs ≤ 2 mm | 3.114 | 1.647-5.888 | 4.757E-4 |
| Ulceration: + vs − | 3.005 | 1.760-5.130 | 5.525E-5 |
| KAI1/p27: ML vs NML | 1.957 | 1.182-3.236 | 0.009 |
CI: confidence interval; ML: metastasis-like subgroup, KAI1-/p27-; NML: non-metastasis-like subgroup: KAI1-/p27+ or KAI1+/p27- or KAI1+/p27+.