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. 2015 Aug 13;6(25):20813–20828. doi: 10.18632/oncotarget.5175

Figure 6. Rab1A is overexpressed in HCC, which is associated with a poor prognosis.

Figure 6

A. Representative immunohistochemistry (IHC) staining images of primary HCC tissues with weak, moderate and high positivity for Rab1A expression, and a representative non-cancerous liver tissue (original magnification, 200×). B. Scatter plots of IHC scores for Rab1A protein expression in HCC and non-cancerous liver tissues in Cohort I. C. Scatter plots of IHC scores for Rab1A protein expression in HCC and non-cancerous liver tissues in Cohort II. D. Immunoblot analysis of Rab1A protein expression in eight pairs of randomly selected HCC and matching non-cancerous liver tissue samples. GAPDH is used as a loading control. E. Rab1A mRNA expression is increased in HCC. Shown is the expression of Rab1A mRNA as determined by analysis of the genomic gene expression profile in 225 HCC and 220 normal liver tissue samples by Roesseler et al. Data is downloaded from OncoMine (www.oncomine.com).