Table 1. Samples’ description.

Diagnosis	Number of Patients	Number of samples per Patient
Normal	14	1 per patient
Glioma	9	1 per patient
Ependimoma	2	1 per patient
Meningioma	4	1 per patient
Glioblastoma	4	1 in 1 patient 3 in 1 patient 6 in 1 patients 7 in 1 patient
Medulloblastoma	3	1 in 1 patient 6 in 1 patient 7 in 1 patient
Lung cancer Metastasis	4	1 in 3 patients 3 in 1 patient
Breast cancer Metastasis	5	1 in 3 patients 4 in 1 patient 6 in 1 patients
Lymphoma	3	1 per patient

Table 1 shows the number of cases (Number of Patients) for each diagnosis (Diagnosis), associated with the number of sample per case collected (Number of samples per Patient). CSF samples from 34 patients with CNS benign and malignant tumors (Gliomas, Ependimomas, Meningiomas, Glioblastomas, Medulloblastomas, Breast and Lung cancer Metastasis to the brain, primary Lymphomas) and from 14 patients without any malignant, or benign lesion, or degenerative disease, affecting the CNS.