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. 2015 May 28;6(25):20829–20839. doi: 10.18632/oncotarget.4096

Table 2. Significant Comparisons among pathology groups.

Up-regulated Group Group2 Fold Change (2^−(ΔΔCt)) p-Value
miR-451 Benign Normal 503.49 < 0.001
Glioblastoma Normal 187.76 < 0.001
Medulloblastoma Normal 62.86 0.002
Metastasis Normal 447.45 < 0.001
miR-711 Benign Lymphoma 2.45 0.058
Glioblastoma Lymphoma 8.77 < 0.001
Medulloblastoma Lymphoma 5.48 < 0.001
Metastasis Lymphoma 3.40 < 0.001
Glioblastoma Medulloblastoma 1.60 0.018
miR-935 Any other group Glioblastoma(not expressed)
Any other group Medulloblastoma(not expressed)
Any other group Lymphoma(not expressed)
Metastasis Benign 1.80 0.007
Lung Metastasis Breast Metastasis 1.69 0.006
miR-223 Glioblastoma Medulloblastoma 3.19 0.031
Glioblastoma Normal 98.05 < 0.001
Medulloblastoma Normal 37.24 < 0.001
Benign Normal 22.20 0.003
Metastasis Normal 32.34 < 0.001
Metastasis Lymphoma 5.60 0.040
Glioblastoma Metastasis 3.03 0.018
miR-125b Medulloblastoma Glioblastoma 3.91 0.001
Medulloblastoma Normal 222.93 < 0.001
Glioblastoma Normal 57.00 < 0.001
Medulloblastoma Lymphoma 14.61 < 0.001
Metastasis Normal 48.45 < 0.001
Metastasis Benign 9.02 < 0.001
Medulloblastoma Metastasis 4.6 0.001

This Table describes the significant comparison that differentiated among pathology groups (Normal, Benign, Glioblastoma, Medulloblastoma, Metastasis: Lung and Breast) for each validated microRNA. Comparisons are reported together with the corresponding fold changes and p-Values with the exception of those comparison in which the entire group had RT-PCR Ct value close or equal to 40 (not expressed).