Table 2. Significant Comparisons among pathology groups.
Up-regulated Group | Group2 | Fold Change (2^−(ΔΔCt)) | p-Value | |
---|---|---|---|---|
miR-451 | Benign | Normal | 503.49 | < 0.001 |
Glioblastoma | Normal | 187.76 | < 0.001 | |
Medulloblastoma | Normal | 62.86 | 0.002 | |
Metastasis | Normal | 447.45 | < 0.001 | |
miR-711 | Benign | Lymphoma | 2.45 | 0.058 |
Glioblastoma | Lymphoma | 8.77 | < 0.001 | |
Medulloblastoma | Lymphoma | 5.48 | < 0.001 | |
Metastasis | Lymphoma | 3.40 | < 0.001 | |
Glioblastoma | Medulloblastoma | 1.60 | 0.018 | |
miR-935 | Any other group | Glioblastoma(not expressed) | ||
Any other group | Medulloblastoma(not expressed) | |||
Any other group | Lymphoma(not expressed) | |||
Metastasis | Benign | 1.80 | 0.007 | |
Lung Metastasis | Breast Metastasis | 1.69 | 0.006 | |
miR-223 | Glioblastoma | Medulloblastoma | 3.19 | 0.031 |
Glioblastoma | Normal | 98.05 | < 0.001 | |
Medulloblastoma | Normal | 37.24 | < 0.001 | |
Benign | Normal | 22.20 | 0.003 | |
Metastasis | Normal | 32.34 | < 0.001 | |
Metastasis | Lymphoma | 5.60 | 0.040 | |
Glioblastoma | Metastasis | 3.03 | 0.018 | |
miR-125b | Medulloblastoma | Glioblastoma | 3.91 | 0.001 |
Medulloblastoma | Normal | 222.93 | < 0.001 | |
Glioblastoma | Normal | 57.00 | < 0.001 | |
Medulloblastoma | Lymphoma | 14.61 | < 0.001 | |
Metastasis | Normal | 48.45 | < 0.001 | |
Metastasis | Benign | 9.02 | < 0.001 | |
Medulloblastoma | Metastasis | 4.6 | 0.001 |
This Table describes the significant comparison that differentiated among pathology groups (Normal, Benign, Glioblastoma, Medulloblastoma, Metastasis: Lung and Breast) for each validated microRNA. Comparisons are reported together with the corresponding fold changes and p-Values with the exception of those comparison in which the entire group had RT-PCR Ct value close or equal to 40 (not expressed).