Table 2. Relationship between PD-L1, HOXB9 and clinico-pathological parameters and their distribution according to variables.
| Cytoplasm | Membrane | Nuclear | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| PD-L1 + | PD-L1 − | p-value | PD-L1 + | PD-L1 − | p-value | HOXB9 + | HOXB9 − | p-value | ||
| Local | Tongue | 11 | 16 | 0.678 | 1 | 26 | n/c | 27 | 4 | 0.775 |
| Floor of the mouth | 14 | 11 | 0 | 25 | 23 | 1 | ||||
| Inferior lip | 6 | 6 | 1 | 11 | 10 | 0 | ||||
| Palate | 3 | 6 | 1 | 8 | 10 | 3 | ||||
| Bucal Mucosa | 4 | 2 | 1 | 5 | 6 | 0 | ||||
| Retromolar trigone | 8 | 5 | 2 | 11 | 11 | 2 | ||||
| Gingiva | 1 | 3 | 1 | 3 | 4 | 0 | ||||
| Gender | Male | 42 | 43 | 0.807 | 7 | 0 | 0.328 | 80 | 10 | 0.248 |
| Female | 5 | 6 | 78 | 11 | 11 | 0 | ||||
| Age | <60 | 32 | 30 | 0.313 | 3 | 59 | 0.216 | 62 | 4 | 0.770 |
| >60 | 15 | 19 | 4 | 30 | 29 | 6 | ||||
| Tumor Size | <4 | 29 | 29 | 0.382 | 3 | 55 | 0.800 | 54 | 6 | 0.192 |
| >4 | 10 | 6 | 3 | 13 | 16 | 0 | ||||
| Smoking | Yes | 38 | 40 | 0.139 | 7 | 71 | 0.306 | 74 | 9 | 0.794 |
| No | 8 | 3 | 0 | 11 | 11 | 1 | ||||
| Alcohol | Yes | 36 | 33 | 0.714 | 7 | 62 | 0.151 | 69 | 4 | 0.002 |
| No | 9 | 10 | 0 | 19 | 15 | 6 | ||||
| Lymph node Metastasis | Yes | 19 | 24 | 0.354 | 4 | 39 | 0.517 | 39 | 4 | 0.950 |
| No | 28 | 24 | 3 | 49 | 51 | 5 | ||||
| Distant Metastasis | Yes | 3 | 3 | 0.979 | 1 | 5 | 0.373 | 6 | 0 | 0.429 |
| No | 44 | 45 | 6 | 86 | 84 | 9 | ||||
| Histological Grading | I | 25 | 21 | 0.204 | 6 | 40 | 0.50 | 39 | 6 | 0.429 |
| II | 18 | 22 | 1 | 39 | 41 | 3 | ||||
| III | 3 | 6 | 0 | 9 | 10 | 1 | ||||