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. 2015 May 21;6(25):21074–21084. doi: 10.18632/oncotarget.4020

Figure 3. Inhibition of WEE1 specifically sensitizes NPC cells compare to nasopharyngeal epithelial cells.

Figure 3

HNE1 and nasopharyngeal epithelial cells (NP460) were exposed to the indicated concentrations of MK-1775 (WEE1i), AZD7762 (CHK1i), VE-821 (ATRi), or KU-60019 (ATMi). After 24 h (for HNE1) or 48 h (for NP460), the cells were harvested and analyzed with flow cytometry. NP460 cells were treated for longer because they have a slower doubling time than the NPC cells. The positions of 2N and 4N DNA contents are indicated.