Skip to main content
. 2015 May 16;6(25):21085–21099. doi: 10.18632/oncotarget.3912

Figure 2. Co-localization of MUC4 and HER3 in pancreatic cancer cells and KPC tumor tissues.

Figure 2

A. Confocal analysis show that MUC4 is strongly co-localized with HER3 in HER2 knockdown CD18/HPAF cells. Further expression of HER2 in HER2 silenced cells and elevated expression of HER3 and MUC4 was observed in CD18/HPAF cells. B. Similarly, Muc4/Her3 co localization was observed in tumor tissues of Kras and p53 (KrasG12D; Trp53R172H−/+; Pdx-1-Cre) mediated pancreatic cancer progression mice model. This results show that co-expression of Muc4/Her3 is relatively higher than Muc4/Her2 in pancreatic cancer progression mice model (10th week, 20th week and 25th week).