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. 2015 May 12;6(25):21137–21147. doi: 10.18632/oncotarget.4121

Figure 2. YM155 treatment downregulated survivin expression in RENCA cells.

Figure 2

A. After treatment with YM155 (50 nM) for 6 and 12 h, whole cell lysates were subjected to Western blot analysis against anti-survivin, AKT, phospho-Akt (Ser 473), phospho-Akt (Thr308), cleaved caspase-3, phospho-c-Raf, and tubulin. B. After 48 h of treatment with YM155, whole cell lysates were subjected to Western blot analysis with the indicated antibodies.