Table 2. Biological characteristics and basal mRNA relative levels of antiapoptotic factors in MCL primary samples.

MCL primary samples	Gender	Age	Disease status	Previous treatment	% tumoral cell	TP53 status	% acadesine Cytotoxicity 2 mM	b mRNA levels
								BCL2	BCLXL
# 1	M	77	D	No	83	wt	a 35.75	2.46	0.78
# 2	M	86	D	No	85	wt	a 19.22	19.96	0.42
# 3	F	78	R	Yes	97	wt	a 90.50	2.79	1.81
# 4	M	83	P	No	89	wt	a 25.71	5.57	1.02
# 5	M	79	D	No	91	del/wt	a 88.80	2.14	0.37
# 6	M	79	D	No	86	del/mut	a 88.71	-	-
# 7	M	79	D	No	86	wt	a 13.01	-	-
# 8	M	57	D	No	80	mut	a 13.25	5.71	3.88
# 9	F	87	D	No	77	mut	a 35.51	-	-
# 10	M	66	D	No	84	del/wt	a 77.30	-	-
# 11	F	63	P	No	77	wt	a 54.30	3.49	0.49
# 12	M	68	R	Yes	76	wt	a 69.21	-	-
# 13	M	81	D	No	97	del/c	a 45.48	-	-
# 14	M	59	D	No	94	wt	a 38.81	2.14	0.56
# 15	M	68	D	No	92	UPD/c	a 29.35	1.24	0.47
# 16	M	89	R	Yes	85	wt	36.75	4.64	0.15
# 17	M	62	D	No	90	del/mut	54.12	2.38	3.19

Abbreviations: D, diagnosis; R, relapse; P, progression; wt, wild type; del, deletion; mut, mutation; UPD, uniparental disomy

^aData from [16]

^bmRNA levels were quantified by qRT-PCR

^cMutations not analyzed