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. 2015 May 19;6(25):21268–21282. doi: 10.18632/oncotarget.4178

Figure 2. A.

Figure 2

Treatment of FaDu and SCC-1 cells with different concentrations of honokiol for 48 h induces apoptosis. Apoptosis was determined using Annexin V-Alexa Fluor488 (Alexa488) Apoptosis Vybrant Assay Kit. Lower right (LR) quadrant indicates the percentage of early apoptotic cells, while Upper right (UR) quadrant indicates the percentage of late apoptotic cells. B. In vitro treatment of FaDu and SCC-1 cells with honokiol for 48 h resulted in a dose-dependent effect on the proteins of Bcl-2 family and cleaved caspase-3, as determined using western blot analysis. C., Effect of honokiol on the proteins of G0/G1 cell cycle phase after the treatment of cells for 48 h.