Table 4.
List of brain regions showing reduced regional brain responses to short-tone burst vestibular stimulation in patients with chronic subjective dizziness (CSD) relative to healthy controls.
Including people with psychiatric conditions | Excluding people with psychiatric conditions | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
P SVC | Z | x | y | z | P SVC | Z | x | y | z | |
Posterior insula R | 0.041 | 3.17 | 44 | −2 | −4 | 0.008 | 3.71 | 44 | 0 | −6 |
PIVC (STg) R | 0.025 | 3.11 | 44 | −16 | −4 | 0.01 | 3.43 | 44 | −16 | −4 |
Ant insula/IFg L | 0.016 | 3.93 | −44 | 12 | 6 | 0.046 | 3.73 | −44 | 14 | 6 |
Hippocampus L | 0.003 | 4.02 | −28 | −18 | −20 | 0.009 | 3.74 | −28 | −18 | −20 |
Hippocampus R | 0.044 | 3.20 | 28 | −16 | −22 | (0.10) | 2.88 | 30 | −16 | −20 |
ACC L | (0.08) | 3.08 | −4 | 44 | 12 | 0.049 | 3.29 | −6 | 44 | 12 |
Cerebellar fastigial nuclei L | 0.02 | 3.03 | −2 | −52 | −32 | (0.13) | 2.24 | −2 | −44 | −26 |
Areas met a threshold of P < 0.05, Family Wise Error, small volume correction for multiple comparison (except for the regions with a not significant P-value reported in Italics in brackets). Z, Z-score; L, left hemisphere; R, right hemisphere; x,y,z, MNI coordinates in millimeters; PIVC, Parieto-Insular Vestibular Cortex; STg, Superior Temporal gyrus; Ant Insula, Anterior Insula; IFg, Inferior Frontal gyrus; ACC, Anterior Cingulate Cortex.