(b).

Gene/rs number	Genotype	T3						T4
		Controls	Patients	Odds ratio	0.95 confidence intervals		p	Controls	Patients	Odds ratio	0.95 confidence intervals		p
		number	number		Lower limit	Upper limit		number	number		Lower limit	Upper limit
DROSHA
6877842	CC	15	4	Ref.				15	1	Ref.
	CG	79	17	0.807	0.238	2.7364	0.4730F	79	21	3.9873	0.4978	31.9386	0.1440F
	GG	76	32	1.5789	0.4863	5.127	0.4424	76	26	5.1316	0.6458	40.776	0.0747F
DICER1
3742330	AA	63	11	Ref.				63	8	Ref.
	AG	103	40	2.2242	1.0641	4.649	0.0308	103	40	3.0583	1.3452	6.9527	0.0058
	GG	4	0	NA				4	0	NA
13078	AA	10	3	Ref.				10	3	Ref.
	AT	124	15	0.4032	0.0997	1.6304	0.1859F	124	15	0.4032	0.0997	1.6304	0.1859F
	TT	36	35	3.2407	0.8222	12.7733	0.0807	36	30	2.7778	0.7001	11.0216	0.1345
DGCR8
1640299	GG	16	2	Ref.				16	3	Ref.
	GT	93	23	1.978	0.4245	9.2218	0.3022F	93	13	0.7455	0.1908	2.9131	0.4531
	TT	61	27	3.541	0.7605	16.4881	0.0739	61	24	2.0984	0.5603	7.8588	0.2067
3757	AA	15	3	Ref.				15	0	Ref.
	AG	119	34	1.4286	0.3905	5.2255	0.4235F	119	34	NA
	GG	36	15	2.0833	0.5251	8.2662	0.2317F	36	11	NA
417309	AA	8	3	Ref.				8	4	Ref.
	AG	46	13	0.7536	0.1745	3.2541	0.4838F	46	9	0.3913	0.0968	1.5817	0.1704F
	GG	116	28	0.6437	0.1604	2.5833	0.3825F	116	31	0.5345	0.151	1.8918	0.2557F
RAN
14035	CC	67	33	Ref.				67	24	Ref.
	CT	93	11	0.2401	0.1133	0.509	<0.0001	93	13	0.3902	0.1854	0.8216	0.0114
	TT	10	3	0.6091	0.157	2.3634	0.3528F	10	1	0.2792	0.0339	2.2978	0.1914F
TARBP2
784567	AA	35	4	Ref.				35	1	Ref.
	AG	114	31	2.3794	0.7857	7.2059	0.1160	114	25	7.6754	1.0036	58.6983	0.0222
	GG	21	19	7.9167	2.3694	26.4517	0.00027	21	22	36.6667	4.6001	292.2647	<0.0001
XPO5
11077	GG	82	10	Ref.				82	11	Ref.
	GT	44	26	4.8455	2.1424	10.9591	<0.0001	44	24	4.0661	1.8231	9.0689	0.000364
	TT	34	16	3.8588	1.5918	9.3545	0.001873	34	12	2.631	1.0584	6.5403	0.033306

^F p values calculated  with Fisher's exact probability test.