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. 2015 Nov 25;2015:298378. doi: 10.1155/2015/298378

Table 4.

An association of the miRNA processing genes single nucleotide polymorphisms with lymph node metastases occurrence in head and neck cancer.

Gene/rs number Genotype Controls
number		 N0 N1–3 N1–3 versus N0
Patients Odds ratio 0.95 confidence intervals p Patients Odds ratio 0.95 confidence intervals p Odds ratio 0.95 confidence intervals p
Number Lower limit Upper limit number Lower limit Upper limit Lower limit Upper limit
DROSHA
6877842 CC 15 6 Ref.       0 Ref.       Ref.      
CG 79 36 1.1392 0.4085 3.1769 0.8064 13 NA       NA      
GG 76 51 1.6776 0.6104 4.611 0.3125 22 NA       NA      
DICER1
3742330 AA 63 18 Ref.       5 Ref.       Ref.      
AG 103 71 2.6041 1.4276 4.7502 0.0014 29 3.5476 1.3057 9.6388 0.0091 1.4704 0.4989 4.3338 0.4839
GG 4 0 NA       0 NA       NA      
13078 AA 10 4 Ref.       3 Ref.       Ref.      
AT 124 38 0.7661 0.2273 2.5825 0.4394F 8 0.2151 0.0492 0.9401 0.0612F 0.2807 0.0523 1.506 0.1470F
TT 36 52 3.6111 1.0503 12.416 0.0331 23 2.1296 0.5292 8.5696 0.2263F 0.5897 0.122 2.85 0.3904F
DGCR8
1640299 GG 16 5 Ref.       1 Ref.       Ref.      
GT 93 34 4.4602 1.6527 12.0368 0.0016 13 8.5269 1.0874 66.8658 0.0159 1.911 0.2035 17.9611 0.493F
TT 61 43 32.787 11.1638 96.2956 <0.0001 17 64.812 8.0116 524.3237 <0.0001 1.976 0.2148 18.1876 0.474F
3757 AA 15 4 Ref.       0 Ref.       Ref.      
AG 119 63 1.9853 0.6321 6.2352 0.2334 26 NA       NA      
GG 36 23 2.3958 0.7068 8.1213 0.1532 6 NA       NA      
417309 AA 8 11 Ref.       2 Ref.       Ref.      
AG 46 25 0.4427 0.1589 1.2335 0.1138 7 0.6087 0.1067 3.4736 0.4382F 1.54 0.2746 8.6355 0.4822F
GG 116 49 0.3072 0.1165 0.8104 0.0131 18 0.6207 0.122 3.1588 0.4176F 2.0204 0.4077 10.013 0.3118F
RAN
14035 CC 67 51 Ref.       22 Ref.       Ref.      
CT 93 28 0.3955 0.2264 0.6909 0.0009 4 0.131 0.0431 0.3977 <0.0001 0.3312 0.1037 1.0573 0.0541
TT 10 4 0.5255 0.1559 1.7718 0.2942 1 0.3045 0.0369 2.5153 0.2253 0.5795 0.0612 5.4857 0.5363
TARBP2
784567 AA 35 7 Ref.       0 Ref.       Ref.      
AG 114 50 2.193 0.9124 5.2711 0.0741 20 NA       NA      
GG 21 36 8.5714 3.2371 22.6961 <0.0001 15 NA       NA      
XPO5
11077 GG 82 19 Ref.       7 Ref.       Ref.      
GT 44 43 4.2177 2.1965 8.099 <0.0001 19 5.0584 1.9743 12.9602 0.0003 1.1993 0.432 3.3294 0.7290
TT 34 28 3.5542 1.7534 7.2043 0.0003 8 2.7563 0.9264 8.2008 0.0599F 0.7755 0.2407 2.4981 0.6713

F p values calculated with Fisher's exact probability test.