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. Author manuscript; available in PMC: 2016 Oct 7.
Published in final edited form as: Mol Pharm. 2015 Nov 4;12(12):4237–4246. doi: 10.1021/acs.molpharmaceut.5b00430

Figure 5.

Figure 5

(A) 2-photon tomographic reconstruction of 4T1/luc tumor, excised immediately after the animal was sacrificed, 24 h post initial injection of LS662, (Green-elastin, blue- collagen, Red-LS662.) Matching fluorescence sectioned histology showing LS662 fluorescence and H&E (B,C, D) Fluorescence (red) and H&E stained images, from a 4T1/luc, A431, and PyMT tumor, respectively. (E) Lymph node infiltrated with tumor cells shows LS662 fluorescence. (F) Muscle samples from 4T1/luc (top), A431 (middle), and PyMT (bottom) bearing mice, show no LS662 fluorescence.