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. 2015 Nov 6;38(11):941–949. doi: 10.14348/molcells.2015.2353

Fig. 2.

Fig. 2.

Rocaglamide-A directly promoted osteoblast differentiation in C2C12 cells. (A) Concentrations of 30 or 50 nM ROC-A significantly promoted ALP activity compared to the bone morphogenetic protein-2 (BMP-2) group (n > 3, *p < 0.05). (B) At a concentration of 50 nM, ROC-A notably promoted the gene expression of ColI, Ocn and Bsp compared to the BMP-2 group (n > 3, *p < 0.05, **p < 0.01). (C) At a concentration of 50 nM, ROC-A promoted the gene expression of Runx2, Osx and ATF4 compared to the BMP-2 group (n > 3, *p < 0.05).