Table 2. The number of differentially expressed genes in two CKD models.
| Samples | Total | Up (%) | Down (%) |
|---|---|---|---|
| WT-GBM vs WT-Nor | 2417 | 1552 (64.21%) | 865 (35.79%) |
| WT-UUO vs WT-Nor | 4959 | 2898 (58.44%) | 2061 (41.56%) |
| Common in two WT models | 1922 | 1203 (62.59%) | 719 (37.41%) |
| KO-GBM vs KO-Nor | 243 | 117 (48.15%) | 126 (51.85%) |
| KO-UUO vs KO-Nor | 735 | 400 (54.42%) | 335 (45.58) |
| Common in two KO models | 84 | 36 (42.86%) | 48 (57.14%) |
Note: WT-GBM:anti-GBM GN model in wild-type mice; WT-Nor:wild-type normal mice; WT-UUO:UUO model in wild-type mice; KO-GBM:anti-GBM GN model in Smad3 knockout mice; KO-UUO:UUO model in Smad3 knockout mice; KO-Nor:Smad3 knockout normal mice; Up:up-regulated genes; Down:down-regulated genes.