Table 3. The number of differentially expressed genes in renal injury related to Smad3.
Comparision | GBM related to Smad3 | UUO related to Smad3 | Common | Gene name |
---|---|---|---|---|
Up in WT & Down in KO | 50 | 17 | 6 | Ighg1, Ighg2c, Igkv12-41, Ighv14-3, Ighv5-6, Ighg2b |
Down in WT & Up in KO | 5 | 22 | 3 | Ugt2b37, Slc22a19, Mfsd2a |
Note: WT:anti-GBM GN or UUO model in wild-type mice; KO:anti-GBM GN or UUO model in Smad3 knockout mice; Up:up-regulated genes; Down:down-regulated genes.