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. 2015 Oct 9;4(10):e44. doi: 10.1038/cti.2015.22

Table 1. Reactivity of anti-LPAP and anti-CD45 mAb with human primary and transformed cells.

  LPAP CD45
Transfectants
 HEK293-mock
 HEK293-LPAP +++
     
Primary cells
 Peripheral blood lymphocytes +++ +++
 Peripheral blood monocytes +++
 Peripheral blood neutrophils ++
 Thymocytes +++ ++
 Monocyte-derived immature dendritic cells  
 Monocyte-derived stimulated dendritic cells  
 Erythrocytes
     
Cell lines
 Jurkat (T-cell leukemia) +++ +++
 CEM (acute T lymphoblastic leukemia) +++ +++
 HUT78 (T cell lymphoma) +++ +++
 MOLT-4 (acute lymphoblastic leukemia) ++ +
 HPB-ALL (T cell lymphoma)
 DAUDI (Burkitt's lymphoma) ++ +++
 Raji (Burkitt's lymphoma) ++ +++
 Ramos (Burkitt's lymphoma) ++ +++
 CCRF-SB (acute lymphoblastic leukemia) + ++
 IM-9 (multiple myeloma) ++ +++
 RPMI 1788 (B lymphocytes) +
 Reh (pro-B leukemia) ++ +++
 NALM-6 (pro-B leukemia)
 RPMI 8266 (myeloma)
 U266 (myeloma) ++
 YT (NK leukemia) +++ +++
 HL-60 (AML-M2) + ++
 THP-1 (AML-M5) ++
 MONO-MAC-6 (AML-M5) +++
 U-937 (histiocytic lymphoma) ++
 K-562 (CML-erythroblast) +++
     
Cell lines (solid tumors)
 Hep G2 (hepatocellular carcinoma)
 MCF7 (adenocarcinoma)

Abbreviation: MFI, mean fluorescence intensity.

Scores: (−) MFI<50; (+) 50<MFI<100; (++) 100<MFI<200; (+++) 200<MFI.