Table 3. Univariate and multivariate analyses of overall survival in various gastric cancer patient subgroups, according to CPCC.
Univariate |
Multivariatea |
|||||
---|---|---|---|---|---|---|
Subgroup | Group | N | HR (95% CI) | P | HR (95% CI) | P |
Male | Group 1 (⩽6) | 107 | 1 | 1 | ||
Group 2 (7–17) | 103 | 0.95 (0.60–1.51) | 0.835 | 0.71 (0.42–1.21) | 0.206 | |
Group 3 (⩾18) | 91 | 1.45 (0.93–2.25) | 0.097 | 1.09 (0.66–1.83) | 0.715 | |
T1 or T2 male | Group 1 (⩽6) | 62 | 1 | 1 | ||
Group 2 (7–17) | 50 | 0.55 (0.17–1.77) | 0.315 | 1.42 (0.38–5.33) | 0.602 | |
Group 3 (⩾18) | 46 | 2.36 (1.02–5.46) | 0.045 | 3.05 (1.06–8.76) | 0.039 | |
T3 or T4 male | Group 1 (⩽6) | 45 | 1 | 1 | ||
Group 2 (7–17) | 53 | 0.83 (0.50–1.37) | 0.461 | 0.75 (0.40–1.43) | 0.386 | |
Group 3 (⩾18) | 45 | 1.05 (0.62–1.77) | 0.854 | 0.88 (0.46–1.66) | 0.684 | |
Female | Group 1 (⩽4) | 50 | 1 | 1 | ||
Group 2 (5–13) | 42 | 1.03 (0.50–2.14) | 0.935 | 1.68 (0.59–4.81) | 0.333 | |
Group 3 (⩾14) | 44 | 0.75 (0.35–1.62) | 0.467 | 0.88 (0.36–2.14) | 0.773 |
Abbreviations: CI, confidence interval; CPCC, chromatin CKAP2 (cytoskeleton-associated protein 2)-positive cell count; HR, hazard regression.
Multivariate analysis with a Cox proportional hazard regression model was used with the co-variables of age, T stage, N stage, histology, tumor location, tumor size, and adjuvant chemotherapy. All patients included in the univariate analysis were also included in the multivariate analysis.
Significant values are shown in bold.