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. 2015 Nov 4;3(11):e12584. doi: 10.14814/phy2.12584

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© 2015 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Body mass and energy and food intake. (A) Body mass throughout the experiment (RM ANOVA, HFD: F_1,28 = 3.09, P = 0.09; LPS: F_2,28 = 2.88, P = 0.07). (B) Total body mass gain 6.5 weeks after the start of the experiment (two-way ANOVA, HFD: F_1,28 = 9.46, P = 0.005; LPS: F_2,28 = 9.46, P = 0.0007). (C) Daily calorie intake (RM two-way ANOVA, HFD: F_1,28 = 54.07, P < 0.0001; LPS: F_2,28 = 21.75, P < 0.0001). (D) Total energy intake at the end of the experiment (two-way ANOVA, HFD: F_1,28 = 28.93, P < 0.0001; LPS: F_2,28 = 11.63, P = 0.0002). (E) Daily food intake (two-way RM ANOVA, HFD: F_1,28 = 2.87, P < 0.0001; LPS: F_2,28 = 1.74, P < 0.0001). (F) Total food intake (two-way ANOVA, HFD: F_1,28 = 102.7, P < 0.0001; LPS: F_2,28 = 17.25, P < 0.0001). Data are presented as means ± SEM (n = 5–6 rats per group). ^# indicates significant effect of LPS, with ^###P < 0.001, and * indicates significant effect of HFD, with ***P < 0.001.