Table 2.
Vehicle | High-fat diet | |||||
---|---|---|---|---|---|---|
Vehicle | LPSlow dose | LPShigh dose | Vehicle | LPSlow dose | LPShigh dose | |
Visceral fat (g)* | 17.51 ± 0.73 | 14.26 ± 0.92 | 16.92 ± 1.41 | 22.02 ± 1.98 | 20.10 ± 1.96 | 21.13 ± 2.11 |
Mesentery fat (g)*,‡ | 3.86 ± 0.21 | 2.78 ± 0.13 | 3.51 ± 0.49 | 4.55 ± 0.48 | 3.73 ± 0.41 | 5.00 ± 0.89 |
Spleen (g)†,‡ | 0.64 ± 0.04 | 0.80 ± 0.07 | 0.92 ± 0.07 | 0.74 ± 0.05 | 0.95 ± 0.07 | 0.95 ± 0.05 |
Liver weight (g) | 9.27 ± 0.36 | 8.88 ± 0.30 | 9.90 ± 0.39 | 8.87 ± 0.56 | 10.23 ± 0.49 | 10.56 ± 0.66 |
Heart (g) | 1.07 ± 0.04 | 1.01 ± 0.04 | 1.08 ± 0.01 | 1.01 ± 0.03 | 1.09 ± 0.05 | 1.12 ± 0.06 |
Pancreas (g) | 1.18 ± 0.10 | 1.30 ± 0.12 | 1.38 ± 0.05 | 1.24 ± 0.16 | 1.36 ± 0.09 | 1.59 ± 0.15 |
Data are presented as means ± SEM (n = 5–6 per group).
Significant effect HFD (high-fat diet, two-way ANOVA, P < 0.05).
Significant effect of LPS (two-way ANOVA, P < 0.05).
Significant effect of LPS (two-way ANCOVA, body mass included as a covariate, P < 0.05).