Table 3.
Study group | ||||||
---|---|---|---|---|---|---|
Patients (n = 15 [Af] and 14 [Un])* | Controls (n = 14) | |||||
Baseline | Hypercapnia | Hypocapnia | Baseline | Hypercapnia | Hypocapnia | |
PETCO2, mmHg | 31.7 ± 4.4 | 37.0 ± 5.1† | 26.2 ± 4.0† | 30.1 ± 5.1 | 35.2 ± 5.4† | 25.1 ± 4.6† |
MCAv, cm sec−1 | Af 42.8 ± 11.9 Un 40.7 ± 13.2 | Af 54.9 ± 17.1† Un 51.9 ± 16.1† | Af 34.7 ± 6.4† Un 33.1 ± 7.0† | 38.1 ± 9.2 | 46.1 ± 11.5† | 32.0 ± 7.3† |
Values are mean ± SD. Baseline refers to the 30 sec immediately preceding the hypercapnia procedure. Hypercapnia and hypocapnia refer to the maximum and minimum PETCO2 respectivley, during CO2 reactivity testing. MCAv data is presented in raw units for ease of interpretation, but was normalised for CO2 reactivity analysis. Af, affected hemisphere; Un, unaffected hemisphere; PETCO2, partial pressure of end-tidal CO2; MCAv, middle cerebral artery flow velocity.
For hypocapnia response. For hypercapnia, n = 14 affected hemisphere and 13 unaffected hemisphere of patients.
P < 0.01 versus baseline.