Table 1.

Body mass, food intake, and terminal uterine weight measurements

	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Body weight (g)
SHAM sed	218.0 ± 3.2a	257.4 ± 4.3a	282.6 ± 4.6a	300.1 ± 5.1a	316.2 ± 5.9a	329.3 ± 6.1a	340.7 ± 5.6a	346.9 ± 6.2a	349.3 ± 6.9a	343.3 ± 7.37a	359.1 ± 11.4a	363.8 ± 10.6a	364.8 ± 11.5a	373.2 ± 10.2a
SHAM ex											355.6 ± 11.2a	355.5 ± 11.6a	359.8 ± 10.0a	381.2 ± 9.9a
OVX sed	237.6 ± 2.4b	294.6 ± 2.9b	345.9 ± 3.9b	361.2 ± 4.4b	381.2 ± 4.5b	394.8 ± 5.2b	403.4 ± 5.8b	402.8 ± 7.2b	417.5 ± 6.0b	417.4 ± 6.0b	407.8 ± 11.9b	400.8 ± 12.0b	486.9 ± 12.1b	421.3 ± 12.9b
OVX E2											416.9 ± 9.7b	410.9 ± 9.9b	407.4 ± 9.5b	417.3 ± 9.9b
OVX ex											427.9 ± 11.7b	408.4 ± 10.7b	421.2 ± 9.6b	437.5 ± 12.8b
Food intake (kcal/day)
SHAM sed	42.3 ± 2.8a	62.6 ± 2.1a	66.1 ± 1.7a	51.1 ± 1.9a	42.0 ± 1.3a	75.2 ± 2.9	69.1 ± 1.4	43.4 ± 1.4	58.5 ± 0.9	49.8 ± 0.5	53.0 ± 4.8ab	37.0 ± 3.9a	42.2 ± 2.3a	44.8 ± 2.0a
SHAM ex											60.9 ± 3.3a	39.9 ± 2.8ab	39.6 ± 1.3ac	40.1 ± 6.5ac
OVX sed	58.1 ± 1.7b	68.9 ± 0.7b	73.1 ± 0.8b	76.7 ± 3.3b	52.8 ± 1.4b	77.3 ± 1.8	68.5 ± 0.7	44.9 ± 1.8	59.6 ± 0.8	50.8 ± 0.4	51.7 ± 4.0ab	47.3 ± 1.5b	37.0 ± 0.6acd	36.6 ± 3.4bc
OVX E2											39.7 ± 2.5b	43.3 ± 1.8ab	34.9 ± 1.6bcd	35.1 ± 1.5bc
OVX ex											46.4 ± 1.3b	45.7 ± 0.9ab	33.6 ± 0.3bd	28.7 ± 1.4b
Uterine weight (g)
SHAM sed														0.89 ± 0.09a
SHAM ex														0.95 ± 0.09a
OVX sed														0.16 ± 0.01b
OVX E2														0.28 ± 0.03b
OVX ex														0.13 ± 0.07b

Data are presented as mean ± standard error, n = 20 and 30 for SHAM and OVX rats from weeks 1 to 10, and n = 10 for all groups from weeks 11 to 14. Groups which share a letter within each parameter within each week are not statistically different, as assessed by unpaired t-test or one-way ANOVA. Statistical significance accepted at P < 0.05.