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. 2015 Nov 24;3(11):e12622. doi: 10.14814/phy2.12622

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© 2015 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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(A) Expression of microRNA-208b in mouse skeletal muscle after electroporation with either microRNA-208b or a control plasmid. (B) Expression of microRNA-499-5p in mouse skeletal muscle after electroporation with either microRNA-499-5p or a control plasmid. (C) Myostatin mRNA 1 week after microRNA-208b overexpression. (D) Myostatin mRNA 1 week after microRNA-499-5p overexpression. n = 6–7 mice, *P < 0.05 for skeletal muscle electroporated with microRNA plasmid (black bars) versus control plasmid (white bars).