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. 2015 Dec 9;5:17956. doi: 10.1038/srep17956

Figure 1. Time course of EP1 expression after cerebral ischemia in rats.

Figure 1

EP1 mRNA expression in the ischemic cortex and EP1 protein levels in the ischemic and contralateral hemispheres were measured in sham-operated and 4, 14, 24, and 48 h after the onset of occlusion. (A) EP1 mRNA is increased at 4 h (P < 0.01, one-way ANOVA) and 48 h after occlusion (P < 0.001, one-way ANOVA) compared to the sham. (B) EP1 protein levels are elevated in the ischemic cortex 14 h after occlusion compared to the sham (P < 0.05, two-tailed unpaired t-test). (C) A representative immunoblot of EP1 expression in the cortex over time in response to ischemia. Sham, N = 5; 4 h, N = 5; 14 h, N = 6; 24 h, N = 8; 48 h, N = 7. CXi = Cortex ipsilateral to stroke; CXc = Cortex contralateral to stroke.