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. 2015 Dec 9;5:17956. doi: 10.1038/srep17956

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Copyright © 2015, Macmillan Publishers Limited

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Mice were subjected to 60 minutes of MCAO occlusion and euthanized 24 h after occlusion. Infarct volume was determined by 2,3,5-triphenyl-2H-tetrazolium chloride staining. Infarct volume is reduced in EP1^−/− mice (23.88 ± 4.008 mm³) compared to the wild-type (28.91 ± 1.428 mm³) although differences are not statistically significant (P = 0.26, unpaired two-tailed t-test). WT, N = 8; EP1^−/−, N = 8. WT = wild-type, EP1^−/− = EP1 knockout.