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The immunohistochemical staining intensity of Collagen type I, Collagen type III and TGF-β1 i n BSA-induced hepatic fibrosis rats
| Group | Dose (mg/kg/day) | n | Collagen type I | Collagen type III | TGF-β1 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| + | ++ | +++ | ++++ | + | ++ | +++ | ++++ | - | + | ++ | +++ | |||
| Normal | — | 12 | 11 | 1 | 0 | 0 | 10 | 2 | 0 | 0 | 12 | 0 | 0 | 0 |
| Model | — | 11 | 0 | 1 | 1 | 9 | 0 | 1 | 2 | 8 | 0 | 1 | 1 | 9 |
| BJRG | 600 | 10 | 2 | 4 | 4 | 0 | 2 | 4 | 3 | 1 | 2 | 5 | 3 | 0 |
| CPhGs | 500 | 12 | 3 | 5 | 3 | 1 | 4 | 4 | 3 | 1 | 3 | 6 | 2 | 1 |
| 250 | 9 | 1 | 4 | 3 | 1 | 2 | 4 | 2 | 1 | 1 | 5 | 2 | 1 | |
| 125 | 10 | 1 | 5 | 1 | 3 | 1 | 5 | 3 | 1 | 2 | 4 | 3 | 1 | |
| Total | 64 | 18 | 20 | 12 | 14 | 19 | 20 | 13 | 12 | 20 | 21 | 11 | 12 | |
