Fig. 1.

The two modules of the stochastic single-cell model. a. Illustration of a model of cell growth with asymmetric division [13]. The cell grows at different rates in the cell cycle stages of G1 and S-G2-M, with the volume increase in S-G2-M being primarily attributable to the daughter compartment. b. The seven stochastic reactions associated with each gene in the network and the rate constants. The promoter switches between ON and OFF states. The ON state promoter is transcribed to produce mRNA, while the OFF state promoter also has some basal, leaky transcription. mRNA is translated to produce protein; and both mRNA and protein can be degraded