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. 2015 Autumn;14(4):989–1000.

Table 4.

Impact of every factor on particle size and PdI of formulations in each design.

Design Particle size
PdI
Positive impact a Negative impact b Positive impact a Negative impact b
1 *C *A, *B, *D *C, *D *B, A
2 *C, *D *A, B *C, *D *A, *B
3 B, *C *A, D *C, *D *A, *B
4 B, *C, D *A *C, D A, B*
5 *C, *D *A, *B *A, *C, *D B*
6 B, D *A, C *A, *C, D B*
*

p < 0.05

a

increasing effect of the factors towards the dependent variables.

b

decreasing effect of the factors towards the dependent variables.