Table 1.
Characteristics of Samples Used in the Discovery and Replication Analyses
| Cases |
Controls |
|||||||
|---|---|---|---|---|---|---|---|---|
| Female, No./Total No. (%) | Type of Stroke, No. (%) |
Female, No./Total No. (%) | ||||||
| Sample | Age Mean (SD), y | Small Vessel | Large Vessel | Cardioembolic | Undetermined | Age, Mean (SD), y | ||
| EA ESP | 312/365 (85.5) | 62.4 (11.6) | 249 (68.2) | 114 (31.2) | 0 | 2 (0.5) | 460/809 (56.9) | 58.5 (11.7) |
|
| ||||||||
| AA ESP | 68/83 (81.9) | 57.0 (9.2) | 57 (68.7) | 23 (27.7) | 0 | 3 (3.6) | 215/317 (67.8) | 59.3 (8.3) |
|
| ||||||||
| SWISS | 36/94 (38.3) | 67.4 (11.5) | 56 (59.6) | 38 (40.4) | 0 | 0 | NA | NA |
|
| ||||||||
| WHI ExomeChip | 1672/1672 (100) | 68.7 (5.8) | 224 (13.4) | 107 (6.4) | 605 (36.2) | 736 (44.0) | 4509/4509 (100) | 66.9 (6.4) |
Abbreviations: AA, African ancestry; EA, European ancestry; ESP, Exome Sequencing Project; NA, not available; SWISS, Siblings With Ischemic Stroke Study; WHI, Women's Health Initiative.