. Author manuscript; available in PMC: 2015 Dec 9.

Published in final edited form as: Mov Disord. 2014 Dec 1;30(2):214–220. doi: 10.1002/mds.26088

Table 2. Effects of CoQ10, statin, and vitamin E on SARA scores in GEE models.

	Regression Coefficient in GEE Models of SARA Scores

	SCA 1	SCA 2	SCA 3	SCA 6
CoQ10 model
CoQ10	−5.90^a	−3.20	−5.54^a	−1.17
Time	0.15^a	0.07	0.05	0.09
CoQ10 × time	−0.05	−0.06	−0.01	−0.05
Statin model
Statin	−1.29	−1.08	−1.26	4.50
Time	0.12^a	0.08	0.06	0.07
Statin × time	0.04	−0.09	−0.07	0.05
Vitamin E model
Vitamin E	−3.09	−1.45	−4.25	−0.22
Time	0.12^a	0.05	0.05	0.06
Vitamin E × Time	0.08	0.11	20.001	0.13

Entries are regression coefficients in the GEE models with the time-varying SARA scores as the outcome of interest and age (year), sex (male/female), pathological CAG repeat number (N), time (month), concurrent medication (Y/N), and its interaction with time as predictors (coefficients of age, sex, and CAG repeat are not shown in the table). The regression coefficients can be interpreted as the change of SARA score per unit change of the predictor variables.

P < 0.01 or the rate of change is significantly different from zero.