Table 2. Effects of CoQ10, statin, and vitamin E on SARA scores in GEE models.
Regression Coefficient in GEE Models of SARA Scores | ||||
---|---|---|---|---|
| ||||
SCA 1 | SCA 2 | SCA 3 | SCA 6 | |
CoQ10 model | ||||
CoQ10 | −5.90a | −3.20 | −5.54a | −1.17 |
Time | 0.15a | 0.07 | 0.05 | 0.09 |
CoQ10 × time | −0.05 | −0.06 | −0.01 | −0.05 |
Statin model | ||||
Statin | −1.29 | −1.08 | −1.26 | 4.50 |
Time | 0.12a | 0.08 | 0.06 | 0.07 |
Statin × time | 0.04 | −0.09 | −0.07 | 0.05 |
Vitamin E model | ||||
Vitamin E | −3.09 | −1.45 | −4.25 | −0.22 |
Time | 0.12a | 0.05 | 0.05 | 0.06 |
Vitamin E × Time | 0.08 | 0.11 | 20.001 | 0.13 |
Entries are regression coefficients in the GEE models with the time-varying SARA scores as the outcome of interest and age (year), sex (male/female), pathological CAG repeat number (N), time (month), concurrent medication (Y/N), and its interaction with time as predictors (coefficients of age, sex, and CAG repeat are not shown in the table). The regression coefficients can be interpreted as the change of SARA score per unit change of the predictor variables.
P < 0.01 or the rate of change is significantly different from zero.