Table 1.
Alteration in LPO (TBARS) and SOD Content in Testis of Control and Treated Animals.
| Groups | LPO (nanomoles of MDA/mg tw/ 60 min) | SOD (units of SOD/mg protein) | |||
|---|---|---|---|---|---|
| Control (A) | 62.5 ± 1.62 | 0.35 ± 0.02 | |||
| Artesunate (150 mg/kg bwt) (B) | 73.3 ± 2.85b | 0.28 ± 0.03b | |||
| Artesunate (300 mg/kg bwt) (C) | 76.6 ± 2.38c | 0.25 ± 0.03c | |||
| Curcumin (80 mg/kg bwt) (D) | 61.1 ± 2.50 NS | 0.37 ± 0.01 NS | |||
| Artesunate (150 mg/kg bwt) + Curcumin (80 mg/kg bwt) (E) | 62.9 ± 3.10 NS | 0.33 ± 0.03 NS | |||
| Artesunate (300 mg/kg bwt) + Curcumin (80 mg/kg bwt) (F) | 67.1 ± 2.47 NS | 0.30 ± 0.02 NS | |||
| Two-way ANOVA | |||||
| Source of Variation | SS | df | MS | F Value | P Value |
| Between the groups (dosage) | 0.2129 | 3 | 0.07097 | 6.041 | .0005 |
| Within the groups (duration) | 4.887 | 416 | 0.01175 | ||
Abbreviations: ANOVA, analysis of variance; bwt, body weight; LPO-TBARS, lipid peroxidation thiobarbutiric acid reactive species; MDA, malonyldialdehyde; SE, standard error; SOD, superoxide dismutase; NS, nonsignificant analysis of variance at P < .05 significance level.
aValues are mean ± SE.
b P < .005.
c P < .001.