Table 3.
Alteration in Oxidative Parameters G-Px and G-Rx Levels in Testis of Control and Treated Animals.a
| Groups | G-Px (GSH Consumed/mg Protein) | G-Rx (Moles NADPH Oxidized/min/mg Protein) | |||
|---|---|---|---|---|---|
| Control (A) | 11.98 ± 0.43 | 0.93 ± 0.14 | |||
| Artesunate (150 mg/kg bwt) (B) | 8.72 ± 0.43b | 0.69 ± 0.03b | |||
| Artesunate (300 mg/kg bwt) (C) | 7.90 ± 0.26c | 0.66 ± 0.04c | |||
| Curcumin (80 mg/kg bwt) (D) | 14.06 ± 0.27 NS | 1.17 ± 0.14 NS | |||
| Artesunate (150 mg/kg bwt) + curcumin (80 mg/kg bwt) (E) | 9.37 ± 0.27 NS | 0.74 ± 0.02 NS | |||
| Artesunate (300 mg/kg bwt) + curcumin (80 mg/kg bwt) (F) | 9.42 ± 0.25 NS | 0.71 ± 0.02 NS | |||
| Two-way ANOVA Analysis | |||||
| Source of Variation | SS | df | MS | F Value | P Value |
| Between the groups (dosage) | 90.64 | 3 | 30.21 | 11.08 | .0001 |
| Within the groups (duration) | 1134 | 416 | 2.726 | ||
Abbreviations: ANOVA, analysis of variance; bwt, body weight; G-Px, glutathione peroxidase; G-Rx, glutathione reductase; GSH, glutathione; GST, glutathione S transferase; NS, nonsignificant analysis of variance at P < .05 significance level; SE, standard deviation.
aValues are mean ± SE.
b P < .005.
c P < .001.