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. 2015 Dec 9;93(6):1274–1284. doi: 10.4269/ajtmh.15-0341

Figure 1.

Figure 1.

Depicted are antibodies expressed as net optical density (OD) (A–C) and ratio OD (D–F) to Plasmodium falciparum circumsporozoite protein (PfCSP), P. falciparum exported protein 1 (PfEXP1), and P. falciparum merozoite surface protein 1 (PfMSP1) by enzyme-linked immunosorbent assay (ELISA) in sera collected 28 days after administration of P. falciparum sporozoite (PfSPZ) Challenge and stratified by group (Group A [10,000 PfSPZ, 2 × 50 μL], B [10,000 PfSPZ, 8 × 50 μL], C [10,000 PfSPZ, 2 × 10 μL], D [10,000 PfSPZ, 8 × 10 μL], E [50,000 PfSPZ, 2 × 10 μL], and F [50,000 PfSPZ, 8 × 10 μL]). The dotted line represents the threshold end point titer ≥ 50, which is considered to be indicative of antibody production. The closed circles represent individuals who did not develop parasitemia. Note: Sera were missing from one aparasitemic volunteer in Group B.