Table 1.
No | Study Name |
Year of publication |
Country | Type | Male: Female |
Single center Vs Multi Center |
N-O scale* |
Cases of CHC |
Genotype | Fibrosis definition |
IR definition |
Total RR (95% CI) |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Hui et al 24 | 2003 | AUS | Case- control | 175:85 | Single | 7 | 260 | 3 and Non 3 | Scheuer | HOMA | 1.3 (1.1– 1.4) |
2 | Sud et al 34 | 2004 | AUS | Cohort | 115:61 | Multi | 6 | 176 | ** | Scheuer | HOMA | 1.47 (1.14– 1.89) |
3 | Bugi anesi et al25 | 2006 | AUS | Cohort | 101:31 | Single | 7 | 132 | 3 | Scheuer | HOMA ≥2.7 | 2.98 (1.13– 7.89) |
4 | Baroni et al 33 | 2007 | Italy | Cohort | 62:28 | Multi | 7 | 90 | 3 and Non 3 | Ishak | HOMA >2.7 | 0.36 (0.06– 2.05) |
5 | Cua et al 21 | 2008 | AUS | Cohort | 235:111 | Single | 5 | 346 | 1 and 3 | Scheuer | HOMA>2 | 3.15 (1.56– 6.35) |
6 | Chu et al 26 | 2008 | China | Cohort | ** | Single | 5 | 192 | ** | Metavir | HOMA >2.5 | 2.46 (1.24– 4.9) |
7 | Petta et al 22 | 2008 | Italy | Cohort | 105:96 | Single | 6 | 201 | 1 | Scheuer | HOMA >2.7 | 2.69 (1.46–4.95) |
8 | Moucari et al 27 | 2008 | France | Cohort | 254:200 | Single | 6 | 454 | 1 and 4 | Metavir | HOMA >3 | 1.8 (1.16– 2.82) |
9 | Halfon et al 29 | 2009 | France | Cohort | 121:49 | Single | 5 | 170 | ** | Metavir | HOMA >2 | 2.44 (1.15–5) |
10 | Moucari et al 28 | 2009 | France | Cohort | 168:58 | Single | 6 | 226 | 4 | Metavir | HOMA>3 | 3.86 (1.86– 8.03) |
11 | Hsu et al 30 | 2010 | Taiwan | Cohort | 288:246 | Single | 5 | 528 | 1 and 2 | Metavir | HOMA >2.4 | 1.23 (0.78– 1.95) |
12 | Patel et al 31 | 2011 | Asia | Cohort | 141:122 | Multi | 5 | 263 | 2 and 3 | Metavir | HOMA>2 | 2.80 (1.4– 5.4) |
13 | Petta et al 23 | 2012 | Italy | Cohort | 239:242 | Single | 5 | 481 | 1 | Scheuer | HOMA>3 | 1.69 (1.04– 2.73) |
14 | Ziada et al 32 | 2013 | Egypt | Case-control | 75:65 | Single | 6 | 140 | ** | HAI | HOMA≥2 | 1.92 (0.97– 3.4) |
Newcastle-Ottawa Scale