The response to tones presented at varying tone intensities was altered in Mecp2 rats compared to control rats in (a) AAF, (b) A1, (c) VAF, and (d) PAF. Across all four fields, Mecp2 rats evoked a weaker response to low intensity tones compared to control rats. However, in AAF and A1, Mecp2 rats also evoked a stronger response to high intensity tones compared to control rats. Error bars indicate SEM across recording sites. Stars indicate a statistically significant difference between Mecp2 rats and control rats (p < 0.0031 Bonferroni corrected). The response at each tone frequency and tone intensity combination is shown in Supplementary Figure 1.