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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Neurobiol Dis. 2015 Aug 28;83:26–34. doi: 10.1016/j.nbd.2015.08.019

Figure 7.

Figure 7

Discrimination of speech sounds in varying levels of background noise is impaired in Mecp2 rats. (a) Rats were tested on their ability to discriminate speech sounds in varying levels of background speech-shaped noise. While there was no significant difference in behavioral accuracy at discriminating speech sounds in quiet (0 dB noise level), Mecp2 rats were significantly impaired at speech sound discrimination in increasing levels of background noise compared to control rats during the first week of training. All speech sounds were presented so that the loudest 100 ms of the vowel was 60 dB. Error bars indicate SEM across rats (n = 5 control rats; n = 5 Mecp2 rats). Stars indicate a statistically significant difference between Mecp2 and control rats (p < 0.05). The dashed line indicates chance performance at 50% correct. Mecp2 rats improved at the speech in noise task, and there was no significant difference in performance between Mecp2 rats and control rats for (b) week 2 or (c) week 3.