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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Mol Cancer Ther. 2015 Oct 29;14(12):2722–2734. doi: 10.1158/1535-7163.MCT-15-0348

Figure 1. Silibinin selectively radiosensitizes PCa cells.

Figure 1

Cells were plated at 600 cells/ well in a 6-well plate and after 24 h treated with the indicated dose of ionizing radiation (IR) and/or 25 μM of silibinin (SB). Cells were then maintained for another 10 days. The colonies were fixed and stained. Number of colonies containing >50 cells were counted and percent colony formation was determined for each cell line with respect to the non-treated controls. Survival curves for (A) advanced human prostate carcinoma DU145 with (B) Representative picture for stained colonies of DU145 cells, (C) PC-3 cells, (D) A549 cells, and (E) transformed non-neoplastic human embryonic kidney, HEK-293 cells are shown. P<0.01 (#), P<0.001(*) compared with respective control