Table 4.
Comparison of positive and negative SLNB patients
| Negative SLNB | Positive SLNB | P value | |
|---|---|---|---|
| Sex (%) | 1.00 | ||
| Male | 88 (22/25) | 85.7 (6/7) | |
| Female | 12 (3/25) | 14.3 (1/7) | |
| Age (y) | |||
| Mean (SD) | 57 (12.9) | 61.5 (14) | .49 |
| Median (range) | 57 (36–91) | 65 (49–78) | |
| Previous skin cancer (%) | 24 (6/25) | 43 (3/7) | .37 |
| BCC | 12 (3/25) | 29 (2/7) | |
| SCC | 4 (1/25) | 14 (1/7) | |
| Melanoma | 8 (2/25) | 0 (0/7) | |
| Side (%) | |||
| Right | 44 (11/25) | 57.1 (4/7) | .68 |
| Left | 56 (14/25) | 42.9 (3/7) | |
| Pathology (%) | .84 | ||
| Superficial spreading | 28 (7/25)* | 14.3 (1/7) | |
| Lentigo | 20 (5/25)* | 14.3 (1/7) | |
| Nodular | 24 (6/25)* | 14.3 (1/7) | |
| Desmoplastic | 8 (2/25) | 14.3 (1/7) | |
| Spindle | 4 (1/25) | 0 (0/7) | |
| Not defined | 24 (6/25) | 42.9 (3/7) | |
| Clark level (%) | 1.00 | ||
| I | 0 (0/25) | 0 (0/7) | |
| II | 0 (0/25) | 0 (0/7) | |
| III | 12 (3/25) | 0 (0/7) | |
| IV | 88 (22/25) | 100 (7/7) | |
| Breslow thickness (mm) | .37 | ||
| Mean (SD) | 2.18 (1.26) | 2.65 (1.15) | |
| Median (range) | 2.1 (.6–5) | 2.15 (1.5–4.4) | |
| Number of nodes removed | .04 | ||
| Mean (SD) | 4.88† (5.88) | 2.14 (1.35) | |
| Median (range) | 3 (1–28) | 2 (1–5) | |
| Postoperative recurrence (%) | 24 (6/25) | 71 (5/7) | .03 |
| Local/regional | 66 (4/6) | 0 (0/7) | |
| Metastatic | 17 (1/6) | 57 (4/7) | |
| Both | 17 (1/6) | 14 (1/7) | |
| Time to recurrence (mo) | .04 | ||
| Mean | 26.4 | 13.4 | |
| Median (range) | 19 (14–43) | 12 (7–23) |
BCC = basal cell carcinoma; SCC = squamous cell carcinoma; SD = standard deviation; SLNB = sentinel lymph node biopsy.
*
One patient had lentiginous and superficial spreading lesions, and 1 patient had lentiginous and nodular lesions.
†
One patient had multiple SLNBs.