Fig. 1.

Summary of method: pooled indirect analysis of IDegLira OD versus other insulin intensification strategies in patients uncontrolled on basal insulin [15, 18–21]. ANCOVA analysis of covariance, BMI body mass index, DPP-4 dipeptidyl peptidase-4 inhibitor, HbA _1c glycated hemoglobin, HDL high-density lipoprotein, IAsp insulin aspart, IDeg insulin degludec, IDegLira insulin degludec/liraglutide, IDet insulin detemir, IGlar insulin glargine, LDL low-density lipoprotein, lira liraglutide, met metformin, OAD oral antidiabetic drug, OD once daily, pio pioglitazone, SBP systolic blood pressure, SU sulfonylurea, TID three-times daily