Table 5.
Results of the main micronucleus test with allyl chloride (for 24 hours)
| Groups | PCE observed | MNPCE observed | MNPCE frequency (%) | PCE + NCE counted | PCE counted | PCE/(PCE + NCE) (%) |
|---|---|---|---|---|---|---|
| Negative control | 2,033.83 ± 19.05 | 3.83 ± 0.98 | 0.19 ± 0.05 | 516.83 ± 13.11 | 325.83 ± 20.07 | 63.03 ± 3.21 |
| 100 mg/kg b.w. | 2,045.50 ± 63.98 | 5.50 ± 3.56 | 0.27 ± 0.18 | 520.00 ± 15.49 | 240.33 ± 36.13 | 46.10 ± 5.60 |
| 200 mg/kg b.w. | 2,048.33 ± 40.90 | 6.17 ± 1.94 | 0.30 ± 0.10 | 510.17 ± 5.81 | 275.17 ± 33.11 | 53.89 ± 5.98 |
| 400 mg/kg b.w. | 2,023.33 ± 13.02 | 7.67 ± 2.07 | 0.38 ± 0.10 | 512.83 ± 14.72 | 239.50 ± 19.69 | 46.74 ± 4.23 |
| Positive control (MMC, 0.5 mg/kg b.w.) |
2,027.00 ± 15.84 | 24.17 ± 4.45 | 1.19 ± 0.22 | 517.50 ± 28.48 | 234.83 ± 59.44 | 45.07 ± 9.03 |
Dats are presented as mean ± the standard deviation.
b.w., body weight; MMC, mitomycin C; MNPCE, micronucleated polychromatic erythrocyte; NCE, normochromatic erythrocyte; PCE, polychromatic erythrocyte.