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. 2015 Feb 17;12(Suppl 1):S37–S43. doi: 10.1016/j.jor.2015.01.020

Table 3.

Treatment of infection with antibiotics.

Microorganism Antimicrobial agent Dosage Route
Staphylococcus aureus coagulate-positive or -negative
Methicillin-susceptible Nafcillin or floxacillin plus 2 g every 6 h IV
Rifampin for 2 weeks followed by 450 mg every 12 h PO
Rifampin plus 450 mg every 12 h PO
Ciprofloxacin or 750 mg every 12 h PO
Levofloxacin 750 mg every 24 h PO
Methicillin-resistant Vancomycin plus 1 g every 12 h IV
Rifampin for 2 weeks 450 mg every 12 h PO
Rifampin plus 450 mg every 12 h PO
Ciprofloxacin or 750 mg every 12 h PO
Levofloxacin or 750 mg every 24 h PO
Teicoplanin or 400 mg every 24 h IV
Fusidic acid 500 mg every 8 h PO
Streptococcus and Enterococcus Penicilln G or 5 million units every 6 h IV
Ampicillin or amoxicillin 2 g every 4–6 h IV
Enterobacter and Actinobacter Ceftazidime or cefepime plus 2 g every 8 h IV
Aminoglycoside for 2 weeks followed by ciprofloxacin 750 mg every 12 h PO
Culture negative Vancomycin plus 1 g every 12 h IV
Ciprofloxacin or 750 mg every 12 h PO
Levofloxacin or 750 mg every 24 h PO
Teicoplanin or 400 mg every 24 h IV
Fusidic acid 500 mg every 8 h PO
Candida albicans Flucorazole 400 mg OD (first day) IV
200 mg OD (from 2nd day) IV
Caspofungin 70 mg OD (first day) IV
50 mg OD (from 2nd day) IV
Mycobacterium tuberculosis Isoniazid 200–400 mg O.D PO
Ethambutol 12 mg/kg O.D PO
Rifampicin 450–600 mg O.D PO
Pyrazinamide 1.5–2.0 g OD or BiD, or TiD PO