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. 2015 Feb 19;16(5):1101–1107. doi: 10.1208/s12249-015-0288-y

Table III.

Summary of Swelling after Needle Removal

3.5 mL/1 min(n = 48) 3.5 mL/4 min(n = 48) 3.5 mL/10 min(n = 48)
Subjects with swelling, n 16 15 12
Swelling height (mm)
 Mean (SD) 1.7 (1.2) 1.6 (0.8) 2.2 (1.2)
 Median (Q1, Q3) 1.0 (1.0, 2.5) 2.0 (1.0, 2.0) 2.0 (1.3, 3.0)
 Range 0.3–5.0 0.5–3.0 0.5–5.0
Swelling diameter (mm)
 Mean (SD) 20.7 (6.2) 19.5 (6.5) 22.9 (5.0)
 Median (Q1, Q3) 20.2 (15.8, 23.1) 19.3 (15.0, 23.1) 22.8 (20.1, 27.1)
 Range 10.8–31.8 6.6–34.1 15.0–31.3
Spread ratio
 Mean (SD) 18.9 (17.7) 15.4 (9.2) 15.6 (13.5)
 Median (Q1, Q3) 14.5 (10.5, 17.6) 10.7 (9.3, 23.1) 11.0 (9.3, 19.8)
 Range 5.9–74.3 6.6–34.1 3.0–53.6
Swelling index
 Mean (SD) 8.0 (4.4) 8.5 (3.9) 10.6 (8.5)
 Median (Q1, Q3) 6.9 (5.7, 9.5) 9.3 (4.3, 10.8) 9.1 (5.1, 10.7)
 Range 1.4–17.1 2.9–15.2 1.9–33.4

LS least square; Q quartile; SD standard deviation; spread ratio = swelling diameter/swelling height; swelling index = 100/spread ratio.