Skip to main content
. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Mol Aspects Med. 2015 Nov 5;46:21–33. doi: 10.1016/j.mam.2015.09.003

Figure 1. Metabolite flux in the control of HGP.

Figure 1

A schematic overview of key enzymes and metabolites involved in the regulation of gluconeogenesis and hepatic glucose output (HGP). Flux through these metabolites is tightly regulated to control net gluconeogenesis or glycolysis. How insulin (blue) or glucagon (red) affect these key enzymes and metabolites is highlighted.